Our Efforts for the Science!!!
The Laboratories located in the Luigi Vanvitelli Campania University of Naples are fully equipped with facilities for extraction and analysis of nucleic acids and proteins, as well as for cell biology analyses and for cell culture, with particular attention to adult stem cells.
We study cellular senescence of mouse and human stem cells. Cellular senescence is the permanent arrest of cell cycle, physiologically related to aging and aging-associated diseases. Senescence is also recognized as a mechanism for limiting the regenerative potential of stem cells and to protect cells from cancer development. We study molecular mechanisms regulating senescence. In detail we are interested in relationship between cell cycle regulation, DNA repair and senescence.